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Differential Transcriptional Effects of EGFR Inhibitors
EGF and its receptor EGFR serve as a paradigm for signaling in cell, molecular and tumor biology. EGFR inhibitors, drugs targeting the intracellular kinase activity and antibodies targeting the extracellular ligand binding, are used to treat breast, lung, colon and other cancers. Nominally affecting...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153546/ https://www.ncbi.nlm.nih.gov/pubmed/25184905 http://dx.doi.org/10.1371/journal.pone.0102466 |