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Epigenome-Wide DNA Methylation in Hearing Ability: New Mechanisms for an Old Problem

Epigenetic regulation of gene expression has been shown to change over time and may be associated with environmental exposures in common complex traits. Age-related hearing impairment is a complex disorder, known to be heritable, with heritability estimates of 57–70%. Epigenetic regulation might exp...

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Detalles Bibliográficos
Autores principales: Wolber, Lisa E., Steves, Claire J., Tsai, Pei-Chien, Deloukas, Panos, Spector, Tim D., Bell, Jordana T., Williams, Frances M. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153547/
https://www.ncbi.nlm.nih.gov/pubmed/25184702
http://dx.doi.org/10.1371/journal.pone.0105729