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Multicenter Study of Trimethoprim/Sulfamethoxazole-Related Hepatotoxicity: Incidence and Associated Factors among HIV-Infected Patients Treated for Pneumocystis jirovecii Pneumonia

The incidence of hepatotoxicity related to trimethoprim/sulfamethoxazole (TMP/SMX) administered at a therapeutic dose may vary among study populations of different ethnicities and hepatotoxic metabolites of TMP/SMX may be decreased by drug-drug interaction with fluconazole. We aimed to investigate t...

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Detalles Bibliográficos
Autores principales: Yang, Jen-Jia, Huang, Chung-Hao, Liu, Chun-Eng, Tang, Hung-Jen, Yang, Chia-Jui, Lee, Yi-Chien, Lee, Kuan-Yeh, Tsai, Mao-Song, Lin, Shu-Wen, Chen, Yen-Hsu, Lu, Po-Liang, Hung, Chien-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153565/
https://www.ncbi.nlm.nih.gov/pubmed/25184238
http://dx.doi.org/10.1371/journal.pone.0106141