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Ameliorative Effect of Fisetin on Cisplatin-Induced Nephrotoxicity in Rats via Modulation of NF-κB Activation and Antioxidant Defence

Nephrotoxicity is a dose-dependent side effect of cisplatin limiting its clinical usage in the field of cancer chemotherapy. Fisetin is a bioactive flavonoid with recognized antioxidant and anti-inflammatory properties. In the present study, we investigated the potential renoprotective effect and un...

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Detalles Bibliográficos
Autores principales: Sahu, Bidya Dhar, Kalvala, Anil Kumar, Koneru, Meghana, Mahesh Kumar, Jerald, Kuncha, Madhusudana, Rachamalla, Shyam Sunder, Sistla, Ramakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153571/
https://www.ncbi.nlm.nih.gov/pubmed/25184746
http://dx.doi.org/10.1371/journal.pone.0105070