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MALDI Imaging Mass Spectrometry Profiling of N-Glycans in Formalin-Fixed Paraffin Embedded Clinical Tissue Blocks and Tissue Microarrays

A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species in frozen tissues has been extended and improved for the direct analysis of glycans in clinically deriv...

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Detalles Bibliográficos
Autores principales: Powers, Thomas W., Neely, Benjamin A., Shao, Yuan, Tang, Huiyuan, Troyer, Dean A., Mehta, Anand S., Haab, Brian B., Drake, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153616/
https://www.ncbi.nlm.nih.gov/pubmed/25184632
http://dx.doi.org/10.1371/journal.pone.0106255