A miRNA Signature of Chemoresistant Mesenchymal Phenotype Identifies Novel Molecular Targets Associated with Advanced Pancreatic Cancer

In this study a microRNA (miRNA) signature was identified in a gemcitabine resistant pancreatic ductal adenocarcinoma (PDAC) cell line model (BxPC3-GZR) and this signature was further examined in advanced PDAC tumor specimens from The Cancer Genome Atlas (TCGA) database. BxPC3-GZR showed a mesenchym...

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Detalles Bibliográficos
Autores principales: Bera, Alakesh, VenkataSubbaRao, Kolaparthi, Manoharan, Muthu Saravanan, Hill, Ping, Freeman, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153643/
https://www.ncbi.nlm.nih.gov/pubmed/25184537
http://dx.doi.org/10.1371/journal.pone.0106343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153643/
https://www.ncbi.nlm.nih.gov/pubmed/25184537
http://dx.doi.org/10.1371/journal.pone.0106343

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