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Antiproliferative Effects and Mechanisms of Liver X Receptor Ligands in Pancreatic Ductal Adenocarcinoma Cells

Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and is often resistant to standard chemotherapeutic options, contributing to extremely poor disease outcomes. Members of the nuclear receptor superfamily carry out essential biological functions such as hormone signaling and are su...

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Detalles Bibliográficos
Autores principales: Candelaria, Nicholes R., Addanki, Sridevi, Zheng, Jine, Nguyen-Vu, Trang, Karaboga, Husna, Dey, Prasenjit, Gabbi, Chiara, Vedin, Lise-Lotte, Liu, Ka, Wu, Wanfu, Jonsson, Philip K., Lin, Jean Z., Su, Fei, Bollu, Lakshmi Reddy, Hodges, Sally E., McElhany, Amy L., Issazadeh, Mehdi A., Fisher, William E., Ittmann, Michael M., Steffensen, Knut R., Gustafsson, Jan-Åke, Lin, Chin-Yo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153644/
https://www.ncbi.nlm.nih.gov/pubmed/25184494
http://dx.doi.org/10.1371/journal.pone.0106289