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Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas

Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system (CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to parallel expression and function in normal stem cells. Using RNA in situ hybridization and antibody tools capable of detectin...

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Detalles Bibliográficos
Autores principales: Holmberg Olausson, Karl, Maire, Cecile L., Haidar, Sam, Ling, Jason, Learner, Emily, Nistér, Monica, Ligon, Keith L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153667/
https://www.ncbi.nlm.nih.gov/pubmed/25184684
http://dx.doi.org/10.1371/journal.pone.0106694