Proliferating Cell Nuclear Antigen Binds DNA Polymerase-β and Mediates 1-Methyl-4-Phenylpyridinium-Induced Neuronal Death

The mechanisms leading to dopaminergic neuronal loss in the substantia nigra of patients with Parkinson disease (PD) remain poorly understood. We recently reported that aberrant DNA replication mediated by DNA polymerase-β (DNA pol-β) plays a causal role in the death of postmitotic neurons in an in...

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Detalles Bibliográficos
Autores principales: Zhang, Zhentao, Zhang, Zhaohui, Wang, Hongcai, Zhang, Guoxin, Hu, Dan, Xiong, Jing, Xiong, Nian, Wang, Tao, Cao, Xuebing, Mao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153671/
https://www.ncbi.nlm.nih.gov/pubmed/25184665
http://dx.doi.org/10.1371/journal.pone.0106669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153671/
https://www.ncbi.nlm.nih.gov/pubmed/25184665
http://dx.doi.org/10.1371/journal.pone.0106669

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