Helicobacter hepaticus Infection Promotes Hepatitis and Preneoplastic Foci in Farnesoid X Receptor (FXR) Deficient Mice

Farnesoid X receptor (FXR) is a nuclear receptor that regulates bile acid metabolism and transport. Mice lacking expression of FXR (FXR KO) have a high incidence of foci of cellular alterations (FCA) and liver tumors. Here, we report that Helicobacter hepaticus infection is necessary for the develop...

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Detalles Bibliográficos
Autores principales: Swennes, Alton G., Sheh, Alexander, Parry, Nicola M. A., Muthupalani, Sureshkumar, Lertpiriyapong, Kvin, García, Alexis, Fox, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153687/
https://www.ncbi.nlm.nih.gov/pubmed/25184625
http://dx.doi.org/10.1371/journal.pone.0106764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153687/
https://www.ncbi.nlm.nih.gov/pubmed/25184625
http://dx.doi.org/10.1371/journal.pone.0106764

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