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Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis

Under conventional conditions, mice deficient in core 1-derived O-glycans (TM-IEC C1galt1(−/−)), which have a defective mucus layer, experienced spontaneous inflammation of the colon. Analysis of fecal bacterial populations by pyrosequencing of 16S rRNA gene showed that disease in conventional TM-IE...

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Detalles Bibliográficos
Autores principales: Perez-Muñoz, Maria Elisa, Bergstrom, Kirk, Peng, Vincent, Schmaltz, Robert, Jimenez-Cardona, Roberto, Marsteller, Nathan, McGee, Sam, Clavel, Thomas, Ley, Ruth, Fu, Jianxin, Xia, Lijun, Peterson, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153765/
https://www.ncbi.nlm.nih.gov/pubmed/24662098
http://dx.doi.org/10.4161/gmic.28622