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Discordance between changes in the gut microbiota and pathogenicity in a mouse model of spontaneous colitis
Under conventional conditions, mice deficient in core 1-derived O-glycans (TM-IEC C1galt1(−/−)), which have a defective mucus layer, experienced spontaneous inflammation of the colon. Analysis of fecal bacterial populations by pyrosequencing of 16S rRNA gene showed that disease in conventional TM-IE...
Autores principales: | Perez-Muñoz, Maria Elisa, Bergstrom, Kirk, Peng, Vincent, Schmaltz, Robert, Jimenez-Cardona, Roberto, Marsteller, Nathan, McGee, Sam, Clavel, Thomas, Ley, Ruth, Fu, Jianxin, Xia, Lijun, Peterson, Daniel A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153765/ https://www.ncbi.nlm.nih.gov/pubmed/24662098 http://dx.doi.org/10.4161/gmic.28622 |
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