Synergetic cytotoxic activity toward breast cancer cells enhanced by the combination of Antp-TPR hybrid peptide targeting Hsp90 and Hsp70-targeted peptide

BACKGROUND: Heat shock protein (Hsp) 90 and Hsp70 are indispensable for cell survival under conditions of stress. They bind to client proteins to assist in protein stabilization, translocation of polypeptides across the cell membrane, and recovery of proteins from aggregates in the cell. Therefore,...

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Detalles Bibliográficos
Autores principales: Horibe, Tomohisa, Torisawa, Aya, Kohno, Masayuki, Kawakami, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153893/
https://www.ncbi.nlm.nih.gov/pubmed/25159299
http://dx.doi.org/10.1186/1471-2407-14-615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153893/
https://www.ncbi.nlm.nih.gov/pubmed/25159299
http://dx.doi.org/10.1186/1471-2407-14-615

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