PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models

BACKGROUND: Hepatocellular carcinoma is the third cause of cancer related death for which new treatment strategies are needed. Targeting DNA repair pathways to sensitize tumor cells to chemo- or radiotherapy is under investigation for the treatment of several cancers with poly(ADP-ribose) polymerase...

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Detalles Bibliográficos
Autores principales: Guillot, Clément, Favaudon, Vincent, Herceg, Zdenko, Sagne, Charlotte, Sauvaigo, Sylvie, Merle, Philippe, Hall, Janet, Chemin, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153905/
https://www.ncbi.nlm.nih.gov/pubmed/25139788
http://dx.doi.org/10.1186/1471-2407-14-603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153905/
https://www.ncbi.nlm.nih.gov/pubmed/25139788
http://dx.doi.org/10.1186/1471-2407-14-603

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