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PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models
BACKGROUND: Hepatocellular carcinoma is the third cause of cancer related death for which new treatment strategies are needed. Targeting DNA repair pathways to sensitize tumor cells to chemo- or radiotherapy is under investigation for the treatment of several cancers with poly(ADP-ribose) polymerase...
Autores principales: | Guillot, Clément, Favaudon, Vincent, Herceg, Zdenko, Sagne, Charlotte, Sauvaigo, Sylvie, Merle, Philippe, Hall, Janet, Chemin, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4153905/ https://www.ncbi.nlm.nih.gov/pubmed/25139788 http://dx.doi.org/10.1186/1471-2407-14-603 |
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