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Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin‐I converting enzyme
Human somatic angiotensin‐I converting enzyme (ACE) is a zinc‐dependent dipeptidyl carboxypeptidase and a central component of the renin angiotensin aldosterone system (RAAS). Its involvement in the modulation of physiological actions of peptide hormones has positioned ACE as an important therapeuti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154125/ https://www.ncbi.nlm.nih.gov/pubmed/24289879 http://dx.doi.org/10.1111/febs.12660 |