A Novel Insertion Mutation on Exon 20 of Epidermal Growth Factor Receptor, Conferring Resistance to Erlotinib

The epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein tyrosine kinase receptor. The small-molecule tyrosine kinase receptor inhibitors (TKIs) are in clinical use to treat non-small cell lung cancer with EGFR mutations. Variable tumor responses to erlotinib and gefitinib have be...

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Detalles Bibliográficos
Autores principales: Khan, Nawazish A., Mirshahidi, Saied, Mirshahidi, Hamid R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Published online: July, 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154193/
https://www.ncbi.nlm.nih.gov/pubmed/25202264
http://dx.doi.org/10.1159/000365325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154193/
https://www.ncbi.nlm.nih.gov/pubmed/25202264
http://dx.doi.org/10.1159/000365325

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