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Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development

The miR-17∼92 cluster family is composed of three members encoding microRNAs that share seed sequences. To assess their role in cerebellar and medulloblastoma (MB) development, we deleted the miR-17∼92 cluster family in Nestin-positive neural progenitors and in mice heterozygous for the Sonic Hedgeh...

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Detalles Bibliográficos
Autores principales: Zindy, Frederique, Kawauchi, Daisuke, Lee, Youngsoo, Ayrault, Olivier, Ben Merzoug, Leila, McKinnon, Peter J., Ventura, Andrea, Roussel, Martine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154296/
https://www.ncbi.nlm.nih.gov/pubmed/24928431
http://dx.doi.org/10.1242/bio.20146734