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An interplay between extracellular signalling and the dynamics of the exit from pluripotency drives cell fate decisions in mouse ES cells

Embryonic Stem cells derived from the epiblast tissue of the mammalian blastocyst retain the capability to differentiate into any adult cell type and are able to self-renew indefinitely under appropriate culture conditions. Despite the large amount of knowledge that we have accumulated to date about...

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Detalles Bibliográficos
Autores principales: Turner, David A., Trott, Jamie, Hayward, Penelope, Rué, Pau, Martinez Arias, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154298/
https://www.ncbi.nlm.nih.gov/pubmed/24950969
http://dx.doi.org/10.1242/bio.20148409