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The Drosophila MCPH1-B isoform is a substrate of the APC(Cdh1) E3 ubiquitin ligase complex
The Anaphase-Promoting Complex (APC) is a multi-subunit E3 ubiquitin ligase that coordinates progression through the cell cycle by temporally and spatially promoting the degradation of key proteins. Many of these targeted proteins have been shown to play important roles in regulating orderly progres...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154303/ https://www.ncbi.nlm.nih.gov/pubmed/24972868 http://dx.doi.org/10.1242/bio.20148318 |