Cargando…

The Drosophila MCPH1-B isoform is a substrate of the APC(Cdh1) E3 ubiquitin ligase complex

The Anaphase-Promoting Complex (APC) is a multi-subunit E3 ubiquitin ligase that coordinates progression through the cell cycle by temporally and spatially promoting the degradation of key proteins. Many of these targeted proteins have been shown to play important roles in regulating orderly progres...

Descripción completa

Detalles Bibliográficos
Autores principales: Hainline, Sarah G., Rickmyre, Jamie L., Neitzel, Leif R., Lee, Laura A., Lee, Ethan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154303/
https://www.ncbi.nlm.nih.gov/pubmed/24972868
http://dx.doi.org/10.1242/bio.20148318