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Cocaine inhibition of nicotinic acetylcholine receptors influences dopamine release

Nicotinic acetylcholine receptors (nAChRs) potently regulate dopamine (DA) release in the striatum and alter cocaine's ability to reinforce behaviors. Since cocaine is a weak nAChR inhibitor, we hypothesized that cocaine may alter DA release by inhibiting the nAChRs in DA terminals in the stria...

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Detalles Bibliográficos
Autores principales: Acevedo-Rodriguez, Alexandra, Zhang, Lifen, Zhou, Fuwen, Gong, Suzhen, Gu, Howard, De Biasi, Mariella, Zhou, Fu-Ming, Dani, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154440/
https://www.ncbi.nlm.nih.gov/pubmed/25237305
http://dx.doi.org/10.3389/fnsyn.2014.00019