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Forward Vaccinology: CTL Targeting Based upon Physical Detection of HLA-Bound Peptides
Vaccine-elicited cytotoxic T lymphocytes (CTL) recognizing conserved fragments of a pathogen’s proteome could greatly impact infectious diseases and cancers. Enabling this potential are recent advances in mass spectrometry that identify specific target peptides among the myriad HLA-bound peptides on...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154463/ https://www.ncbi.nlm.nih.gov/pubmed/25237310 http://dx.doi.org/10.3389/fimmu.2014.00418 |