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Forward Vaccinology: CTL Targeting Based upon Physical Detection of HLA-Bound Peptides

Vaccine-elicited cytotoxic T lymphocytes (CTL) recognizing conserved fragments of a pathogen’s proteome could greatly impact infectious diseases and cancers. Enabling this potential are recent advances in mass spectrometry that identify specific target peptides among the myriad HLA-bound peptides on...

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Detalles Bibliográficos
Autores principales:	Reinherz, Ellis L., Keskin, Derin B., Reinhold, Bruce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154463/ https://www.ncbi.nlm.nih.gov/pubmed/25237310 http://dx.doi.org/10.3389/fimmu.2014.00418

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