Loss of breast epithelial marker hCLCA2 promotes epithelial to mesenchymal transition and indicates higher risk of metastasis

Transition between epithelial and mesenchymal states is a feature of both normal development and tumor progression. We report that expression of chloride channel accessory protein hCLCA2 is a characteristic of epithelial differentiation in the immortalized MCF10A and HMLE models, while induction of...

Descripción completa

Detalles Bibliográficos
Autores principales: Walia, Vijay, Yu, Yang, Cao, Deshou, Sun, Miao, McLean, Janel R., Hollier, Brett G., Cheng, Jiming, Mani, Sendurai A., Rao, Krishna, Premkumar, Louis, Elble, Randolph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154589/
https://www.ncbi.nlm.nih.gov/pubmed/21909135
http://dx.doi.org/10.1038/onc.2011.392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154589/
https://www.ncbi.nlm.nih.gov/pubmed/21909135
http://dx.doi.org/10.1038/onc.2011.392

Ejemplares similares