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Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products

Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of great biomedical importance, including antibiotics such as penicillin, immunosuppressants such as cyclosporine, and cytostatics such as bleomycin. Recently, an innovative mass-spectrometry-based strateg...

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Detalles Bibliográficos
Autores principales: Medema, Marnix H., Paalvast, Yared, Nguyen, Don D., Melnik, Alexey, Dorrestein, Pieter C., Takano, Eriko, Breitling, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154637/
https://www.ncbi.nlm.nih.gov/pubmed/25188327
http://dx.doi.org/10.1371/journal.pcbi.1003822