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Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products
Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of great biomedical importance, including antibiotics such as penicillin, immunosuppressants such as cyclosporine, and cytostatics such as bleomycin. Recently, an innovative mass-spectrometry-based strateg...
Autores principales: | Medema, Marnix H., Paalvast, Yared, Nguyen, Don D., Melnik, Alexey, Dorrestein, Pieter C., Takano, Eriko, Breitling, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154637/ https://www.ncbi.nlm.nih.gov/pubmed/25188327 http://dx.doi.org/10.1371/journal.pcbi.1003822 |
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