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Dynamic Conformational Change Regulates the Protein-DNA Recognition: An Investigation on Binding of a Y-Family Polymerase to Its Target DNA

Protein-DNA recognition is a central biological process that governs the life of cells. A protein will often undergo a conformational transition to form the functional complex with its target DNA. The protein conformational dynamics are expected to contribute to the stability and specificity of DNA...

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Detalles Bibliográficos
Autores principales: Chu, Xiakun, Liu, Fei, Maxwell, Brian A., Wang, Yong, Suo, Zucai, Wang, Haijun, Han, Wei, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154647/
https://www.ncbi.nlm.nih.gov/pubmed/25188490
http://dx.doi.org/10.1371/journal.pcbi.1003804