Revealing Molecular Mechanisms by Integrating High-Dimensional Functional Screens with Protein Interaction Data

Functional genomics screens using multi-parametric assays are powerful approaches for identifying genes involved in particular cellular processes. However, they suffer from problems like noise, and often provide little insight into molecular mechanisms. A bottleneck for addressing these issues is th...

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Detalles Bibliográficos
Autores principales: Simeone, Angela, Marsico, Giovanni, Collinet, Claudio, Galvez, Thierry, Kalaidzidis, Yannis, Zerial, Marino, Beyer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154648/
https://www.ncbi.nlm.nih.gov/pubmed/25188415
http://dx.doi.org/10.1371/journal.pcbi.1003801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154648/
https://www.ncbi.nlm.nih.gov/pubmed/25188415
http://dx.doi.org/10.1371/journal.pcbi.1003801

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