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Revealing Molecular Mechanisms by Integrating High-Dimensional Functional Screens with Protein Interaction Data
Functional genomics screens using multi-parametric assays are powerful approaches for identifying genes involved in particular cellular processes. However, they suffer from problems like noise, and often provide little insight into molecular mechanisms. A bottleneck for addressing these issues is th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154648/ https://www.ncbi.nlm.nih.gov/pubmed/25188415 http://dx.doi.org/10.1371/journal.pcbi.1003801 |