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Prognostic Significance of Overexpressed p16(INK4a) in Patients with Cervical Cancer: A Meta-Analysis
BACKGROUND: p16(INK4a) is a tumor suppressor protein which is induced in cells upon the interaction of high-risk HPV E7 with the retinoblastoma protein by a positive feedback loop, but cannot exert its suppressing effect. Previous reports suggested that p16(INK4a) immunostaining allows precise ident...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154680/ https://www.ncbi.nlm.nih.gov/pubmed/25188353 http://dx.doi.org/10.1371/journal.pone.0106384 |