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Prognostic Significance of Overexpressed p16(INK4a) in Patients with Cervical Cancer: A Meta-Analysis

BACKGROUND: p16(INK4a) is a tumor suppressor protein which is induced in cells upon the interaction of high-risk HPV E7 with the retinoblastoma protein by a positive feedback loop, but cannot exert its suppressing effect. Previous reports suggested that p16(INK4a) immunostaining allows precise ident...

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Detalles Bibliográficos
Autores principales: Lin, Jiaying, Albers, Andreas E., Qin, Jinbao, Kaufmann, Andreas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154680/
https://www.ncbi.nlm.nih.gov/pubmed/25188353
http://dx.doi.org/10.1371/journal.pone.0106384