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A Semi-Dominant Mutation in the General Splicing Factor SF3a66 Causes Anterior-Posterior Axis Reversal in One-Cell Stage C. elegans Embryos
Establishment of anterior-posterior polarity in one-cell stage Caenorhabditis elegans embryos depends in part on astral microtubules. As the zygote enters mitosis, these microtubules promote the establishment of a posterior pole by binding to and protecting a cytoplasmic pool of the posterior polari...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154684/ https://www.ncbi.nlm.nih.gov/pubmed/25188372 http://dx.doi.org/10.1371/journal.pone.0106484 |