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Quantification of Protein Copy Number in Yeast: The NAD(+) Metabolome
Saccharomyces cerevisiae is calorie-restricted by lowering glucose from 2% to 0.5%. Under low glucose conditions, replicative lifespan is extended in a manner that depends on the NAD(+)-dependent protein lysine deacetylase Sir2 and NAD(+) salvage enzymes. Because NAD(+) is required for glucose utili...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154715/ https://www.ncbi.nlm.nih.gov/pubmed/25188219 http://dx.doi.org/10.1371/journal.pone.0106496 |