PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation

cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA function can be achieved by discrete compartmentalization of the enzyme via physical interaction with A-kinase anchoring proteins (AKAPs). Here, we investigated the role...

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Detalles Bibliográficos
Autores principales: Radeva, Mariya Y., Kugelmann, Daniela, Spindler, Volker, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154725/
https://www.ncbi.nlm.nih.gov/pubmed/25188285
http://dx.doi.org/10.1371/journal.pone.0106733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154725/
https://www.ncbi.nlm.nih.gov/pubmed/25188285
http://dx.doi.org/10.1371/journal.pone.0106733

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