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PKA Compartmentalization via AKAP220 and AKAP12 Contributes to Endothelial Barrier Regulation
cAMP-mediated PKA signaling is the main known pathway involved in maintenance of the endothelial barrier. Tight regulation of PKA function can be achieved by discrete compartmentalization of the enzyme via physical interaction with A-kinase anchoring proteins (AKAPs). Here, we investigated the role...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154725/ https://www.ncbi.nlm.nih.gov/pubmed/25188285 http://dx.doi.org/10.1371/journal.pone.0106733 |