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Amplification Biases and Consistent Recovery of Loci in a Double-Digest RAD-seq Protocol
A growing variety of “genotype-by-sequencing” (GBS) methods use restriction enzymes and high throughput DNA sequencing to generate data for a subset of genomic loci, allowing the simultaneous discovery and genotyping of thousands of polymorphisms in a set of multiplexed samples. We evaluated a “doub...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154734/ https://www.ncbi.nlm.nih.gov/pubmed/25188270 http://dx.doi.org/10.1371/journal.pone.0106713 |