Efficient Gene Knockout in Goats Using CRISPR/Cas9 System

The CRISPR/Cas9 system has been adapted as an efficient genome editing tool in laboratory animals such as mice, rats, zebrafish and pigs. Here, we report that CRISPR/Cas9 mediated approach can efficiently induce monoallelic and biallelic gene knockout in goat primary fibroblasts. Four genes were dis...

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Detalles Bibliográficos
Autores principales: Ni, Wei, Qiao, Jun, Hu, Shengwei, Zhao, Xinxia, Regouski, Misha, Yang, Min, Polejaeva, Irina A., Chen, Chuangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154755/
https://www.ncbi.nlm.nih.gov/pubmed/25188313
http://dx.doi.org/10.1371/journal.pone.0106718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154755/
https://www.ncbi.nlm.nih.gov/pubmed/25188313
http://dx.doi.org/10.1371/journal.pone.0106718

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