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Synergistic Anti-Inflammatory Activity of the Antimicrobial Peptides Human Beta-Defensin-3 (hBD-3) and Cathelicidin (LL-37) in a Three-Dimensional Co-Culture Model of Gingival Epithelial Cells and Fibroblasts

Given the spread of antibiotic resistance in bacterial pathogens, antimicrobial peptides that can also modulate the immune response may be a novel approach for effectively controlling periodontal infections. In the present study, we used a three-dimensional (3D) co-culture model of gingival epitheli...

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Detalles Bibliográficos
Autores principales: Bedran, Telma Blanca Lombardo, Mayer, Márcia Pinto Alves, Spolidorio, Denise Palomari, Grenier, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154759/
https://www.ncbi.nlm.nih.gov/pubmed/25187958
http://dx.doi.org/10.1371/journal.pone.0106766