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Functional Changes in Pulmonary Arterial Endothelial Cells Associated with BMPR2 Mutations

Pulmonary arterial hypertension (PAH) is a devastating disease characterized by abnormal remodeling of small, peripheral pulmonary arteries. Germline mutations in the bone morphogenetic protein receptor type 2 (BMPR2) gene are a major risk factor for developing PAH. At present, the correlation betwe...

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Detalles Bibliográficos
Autores principales: Wang, Hu, Ji, Ruirui, Meng, Jie, Cui, Qiqiong, Zou, Wenxin, Li, Lei, Wang, Guoliang, Sun, Li, Li, Zhaohui, Huo, Lei, Fan, Yuxin, Penny, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154762/
https://www.ncbi.nlm.nih.gov/pubmed/25187962
http://dx.doi.org/10.1371/journal.pone.0106703