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Crystal Structure of the Mineralocorticoid Receptor DNA Binding Domain in Complex with DNA

The steroid hormone receptors regulate important physiological functions such as reproduction, metabolism, immunity, and electrolyte balance. Mutations within steroid receptors result in endocrine disorders and can often drive cancer formation and progression. Despite the conserved three-dimensional...

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Detalles Bibliográficos
Autores principales: Hudson, William H., Youn, Christine, Ortlund, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154765/
https://www.ncbi.nlm.nih.gov/pubmed/25188500
http://dx.doi.org/10.1371/journal.pone.0107000