The gp120 Protein Is a Second Determinant of Decreased Neurovirulence of Indian HIV-1C Isolates Compared to Southern African HIV-1C Isolates

Regional differences in neurovirulence have been documented among subtype/clade-C HIV-1 isolates in India and Southern Africa. We previously demonstrated that a C31S substitution in Clade-C Tat dicysteine motif reduces monocyte recruitment, cytokine induction and direct neurotoxicity. Therefore, thi...

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Detalles Bibliográficos
Autores principales: Rao, Vasudev R., Neogi, Ujjwal, Eugenin, Eliseo, Prasad, Vinayaka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154767/
https://www.ncbi.nlm.nih.gov/pubmed/25188269
http://dx.doi.org/10.1371/journal.pone.0107074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154767/
https://www.ncbi.nlm.nih.gov/pubmed/25188269
http://dx.doi.org/10.1371/journal.pone.0107074

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