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Near-Term Anti-CD25 Monoclonal Antibody Administration Protects Murine Liver from Ischemia-Reperfusion Injury Due to Reduced Numbers of CD4(+) T Cells

BACKGROUND: CD4(+) T cell is acknowledged as a key factor in the initiation phase of liver ischemia reperfusion injury. The purpose of current study is to demonstrate the effect of antecedent near-term anti-CD25 monoclonal antibody treatment on IR-induced liver injury by modulation of CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Yang, Jinghui, Wang, Xiaoyu, Song, Shaohua, Liu, Fang, Fu, Zhiren, Wang, Quanxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154778/
https://www.ncbi.nlm.nih.gov/pubmed/25188007
http://dx.doi.org/10.1371/journal.pone.0106892