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Delineation of Interfaces on Human Alpha-Defensins Critical for Human Adenovirus and Human Papillomavirus Inhibition

Human α-defensins are potent anti-microbial peptides with the ability to neutralize bacterial and viral targets. Single alanine mutagenesis has been used to identify determinants of anti-bacterial activity and binding to bacterial proteins such as anthrax lethal factor. Similar analyses of α-defensi...

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Detalles Bibliográficos
Autores principales: Tenge, Victoria R., Gounder, Anshu P., Wiens, Mayim E., Lu, Wuyuan, Smith, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154873/
https://www.ncbi.nlm.nih.gov/pubmed/25188351
http://dx.doi.org/10.1371/journal.ppat.1004360