Cargando…

Mouse, but Not Human, ApoB-100 Lipoprotein Cholesterol Is a Potent Innate Inhibitor of Streptococcus pneumoniae Pneumolysin

Streptococcus pneumoniae produces the pore-forming toxin pneumolysin (PLY), which is a member of the cholesterol-dependent cytolysin (CDC) family of toxins. The CDCs recognize and bind the 3β-hydroxyl group of cholesterol at the cell surface, which initiates membrane pore formation. The cholesterol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wade, Kristin R., Hotze, Eileen M., Briles, David E., Tweten, Rodney K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154877/ https://www.ncbi.nlm.nih.gov/pubmed/25188225 http://dx.doi.org/10.1371/journal.ppat.1004353

Ejemplares similares

The Impact of Pneumolysin on the Macrophage Response to Streptococcus pneumoniae is Strain-Dependent
por: Harvey, Richard M., et al.
Publicado: (2014)

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation
por: Lawrence, Sara L., et al.
Publicado: (2015)

Investigation of human apoB48 metabolism using a new, integrated non‐steady‐state model of apoB48 and apoB100 kinetics
por: Björnson, E., et al.
Publicado: (2019)

SAA is Found on ApoB-Containing Lipoproteins in Obese Diabetic Humans
por: Jahangiri, Anisa, et al.
Publicado: (2013)

Comparison of Apolipoprotein (apoB/apoA-I) and Lipoprotein (Total Cholesterol/HDL) Ratio Determinants. Focus on Obesity, Diet and Alcohol Intake
por: Tognon, Gianluca, et al.
Publicado: (2012)

Uptake of (68)gallium in atherosclerotic plaques in LDLR(-/-)ApoB(100/100 )mice
por: Silvola, Johanna MU, et al.
Publicado: (2011)

ApoB and Non‐HDL Cholesterol Versus LDL Cholesterol for Ischemic Stroke Risk
por: Johannesen, Camilla D. L., et al.
Publicado: (2022)

Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE(-/-) mice
por: Dunér, Pontus, et al.
Publicado: (2021)

Biosynthesis of lipoprotein: location of nascent apoAI and apoB in the rough endoplasmic reticulum of chicken hepatocytes
Publicado: (1992)

Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromised
por: Basu, Debapriya, et al.
Publicado: (2015)

Atheroprotective Vaccination with MHC-II Restricted Peptides from ApoB-100
por: Tse, Kevin, et al.
Publicado: (2013)

Identification of apoB‐100 Peptide‐Specific CD8+ T Cells in Atherosclerosis
por: Dimayuga, Paul C., et al.
Publicado: (2017)

Biphasic Production of Anti-ApoB100 Autoantibodies in Obese Humans and Mice
por: Choe, Moon Kyung, et al.
Publicado: (2021)

Immunization using ApoB-100 peptide–linked nanoparticles reduces atherosclerosis
por: Chyu, Kuang-Yuh, et al.
Publicado: (2022)

Western Diet Decreases Hepatic Drug Metabolism in Male LDLr(−/−)ApoB(100/100) Mice
por: Koponen, Markus, et al.
Publicado: (2023)

Autoantibodies Against ApoB-100 as a New Marker of Coronary Vulnerable Plaque
por: Egusa, Genshi
Publicado: (2021)

Potential role of ATM in hepatocyte endocytosis of ApoE-deficient, ApoB48-containing lipoprotein in ApoE-deficient mice
por: WU, JIANHUA, et al.
Publicado: (2014)

ApoA-I/A-II-HDL positively associates with apoB-lipoproteins as a potential atherogenic indicator
por: Kido, Toshimi, et al.
Publicado: (2017)

ApoB48-Lipoproteins Are Associated with Cardiometabolic Risk in Adolescents with and without Polycystic Ovary Syndrome
por: Vine, Donna F, et al.
Publicado: (2020)

Streptococcus pneumoniae pneumolysin and neuraminidase A convert high-density lipoproteins into pro-atherogenic particles
por: Syed, Shahan, et al.
Publicado: (2021)

CD8(+) T Cells Mediate the Athero-Protective Effect of Immunization with an ApoB-100 Peptide
por: Chyu, Kuang-Yuh, et al.
Publicado: (2012)

Increased Tau Phosphorylation and Impaired Presynaptic Function in Hypertriglyceridemic ApoB-100 Transgenic Mice
por: Lénárt, Nikolett, et al.
Publicado: (2012)

Chlamydia pneumoniae Infection Exacerbates Atherosclerosis in ApoB100only/LDLR(−/−) Mouse Strain
por: Lantos, Ildikó, et al.
Publicado: (2018)

Cerebrovascular Changes and Neurodegeneration Related to Hyperlipidemia: Characteristics of the Human ApoB-100 Transgenic Mice
por: Tóth, Melinda E., et al.
Publicado: (2020)

Echium Oil Reduces Plasma Triglycerides by Increasing Intravascular Lipolysis in apoB100-Only Low Density Lipoprotein (LDL) Receptor Knockout Mice
por: Forrest, Lolita M., et al.
Publicado: (2013)

ApoB-100 Lipoprotein Complex Formation with Intima Proteoglycans as a Cause of Atherosclerosis and Its Possible Ex Vivo Evaluation as a Disease Biomarker
por: Hurt-Camejo, Eva, et al.
Publicado: (2018)

Regulation of plasma LDL: the apoB paradigm
por: Sniderman, Allan D., et al.
Publicado: (2009)

Proteoglycan binding as proatherogenic function metric of apoB-containing lipoproteins and chronic kidney graft failure
por: Steffen, Hannah L.M., et al.
Publicado: (2021)

ApoB100/LDLR-/- Hypercholesterolaemic Mice as a Model for Mild Cognitive Impairment and Neuronal Damage
por: Ramírez, Carlos, et al.
Publicado: (2011)

Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets
por: Suzuki, Michitaka, et al.
Publicado: (2012)

Subjects with Molecularly Defined Familial Hypercholesterolemia or Familial Defective apoB-100 Are Not Being Adequately Treated
por: Leren, Trond P., et al.
Publicado: (2011)

Roles of ApoB-100 Gene Polymorphisms and the Risks of Gallstones and Gallbladder Cancer: A Meta-Analysis
por: Gong, Yi, et al.
Publicado: (2013)

Glycosyltransferase GLT8D2 Positively Regulates ApoB100 Protein Expression in Hepatocytes
por: Wei, Hong-Shan, et al.
Publicado: (2013)

T-Cells Specific for a Self-Peptide of ApoB-100 Exacerbate Aortic Atheroma in Murine Atherosclerosis
por: Shaw, Michael K., et al.
Publicado: (2017)

Evidence for Beneficial Associations between Isoenergetic Macronutrient Exchanges and Serum non-HDL Cholesterol, a Measure of All Circulating Atherogenic, apoB-Containing Lipoproteins
por: Griffin, Bruce A, et al.
Publicado: (2021)

Preclinical in vitro and in vivo profile of a highly-attenuated, broadly efficacious pneumolysin genetic toxoid
por: Thanawastien, Ann, et al.
Publicado: (2020)

The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels
por: Drouin-Chartier, Jean-Philippe, et al.
Publicado: (2017)

Racial differences between African-American and white women in insulin resistance and visceral adiposity are associated with differences in apoCIII containing apoAI and apoB lipoproteins
por: Wang, Liyun, et al.
Publicado: (2014)

Pyruvate oxidase of Streptococcus pneumoniae contributes to pneumolysin release
por: Bryant, Joseph C., et al.
Publicado: (2016)

Non-invasive skin cholesterol testing: a potential proxy for LDL-C and apoB serum measurements
por: Lai, Jiacheng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hu6ja1iaj1lh1q6m2sgpgd1i6b