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The involvement of Kras gene 3′-UTR polymorphisms in risk of cancer and influence on patient response to anti-EGFR therapy in metastatic colorectal cancer: a meta-analysis

BACKGROUND: Genetic variation of the Kras oncogene is a candidate factor for increasing susceptibility to carcinoma and modulating response of metastatic colorectal cancer (mCRC) patients treated with anti-epidermal growth factor receptor monoclonal antibody (anti-EGFR). However, results from an inc...

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Detalles Bibliográficos
Autores principales: Ying, Hou-Qun, Wang, Feng, He, Bang-Shun, Pan, Yu-Qin, Gao, Tian-Yi, Xu, Ye-Qiong, Li, Rui, Deng, Qi-Wen, Sun, Hui-Lin, Wang, Shu-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154892/
https://www.ncbi.nlm.nih.gov/pubmed/25210463
http://dx.doi.org/10.2147/OTT.S65496