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Generation of improved humanized mouse models for human infectious diseases

The study of human-specific infectious agents has been hindered by the lack of optimal small animal models. More recently development of novel strains of immunodeficient mice has begun to provide the opportunity to utilize small animal models for the study of many human-specific infectious agents. T...

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Detalles Bibliográficos
Autores principales: Brehm, Michael A., Wiles, Michael V., Greiner, Dale L., Shultz, Leonard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155027/
https://www.ncbi.nlm.nih.gov/pubmed/24607601
http://dx.doi.org/10.1016/j.jim.2014.02.011