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Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer
BACKGROUND: Ovarian tumors create a dynamic microenvironment that promotes angiogenesis and reduces immune responses. Our research has revealed that threonyl-tRNA synthetase (TARS) has an extracellular angiogenic activity separate from its function in protein synthesis. The objective of this study w...
Autores principales: | Wellman, Theresa L, Eckenstein, Midori, Wong, Cheung, Rincon, Mercedes, Ashikaga, Takamaru, Mount, Sharon L, Francklyn, Christopher S, Lounsbury, Karen M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155084/ https://www.ncbi.nlm.nih.gov/pubmed/25163878 http://dx.doi.org/10.1186/1471-2407-14-620 |
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