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MiR-181b sensitizes glioma cells to teniposide by targeting MDM2

BACKGROUND: Although the incidence of glioma is relatively low, it is the most malignant tumor of the central nervous system. The prognosis of high-grade glioma patient is very poor due to the difficulties in complete resection and resistance to radio-/chemotherapy. Therefore, it is worth investigat...

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Detalles Bibliográficos
Autores principales: Sun, Yan-chang, Wang, Jing, Guo, Cheng-cheng, Sai, Ke, Wang, Jian, Chen, Fu-rong, Yang, Qun-ying, Chen, Yin-sheng, Wang, Jie, To, Tony Shing-shun, Zhang, Zong-ping, Mu, Yong-gao, Chen, Zhong-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155117/
https://www.ncbi.nlm.nih.gov/pubmed/25151861
http://dx.doi.org/10.1186/1471-2407-14-611