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Transcription factor-pathway co-expression analysis reveals cooperation between SP1 and ESR1 on dysregulating cell cycle arrest in non-hyperdiploid multiple myeloma

Multiple myeloma is a hematological cancer of plasma B-cells and remains incurable. Two major subtypes of myeloma, hyperdiploid (HMM) and non-hyperdiploid myeloma (NHMM), have distinct chromosomal alterations and different survival outcomes. Transcription factors (TrFs) have been implicated in myelo...

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Detalles Bibliográficos
Autores principales: Wang, Xujun, Yan, Zhenyu, Fulciniti, Mariateresa, Li, Yingxiang, Gkotzamanidou, Maria, Amin, Samir B, Shah, Parantu K, Zhang, Yong, Munshi, Nikhil C, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155324/
https://www.ncbi.nlm.nih.gov/pubmed/23925045
http://dx.doi.org/10.1038/leu.2013.233