Germline Mutation of RPS20, Encoding a Ribosomal Protein, Causes Predisposition to Hereditary Nonpolyposis Colorectal Carcinoma Without DNA Mismatch Repair Deficiency

Little is known about the genetic factors that contribute to familial colorectal cancer type X (FCCX), characterized by hereditary nonpolyposis colorectal carcinoma with no mismatch repair defects. Genetic linkage analysis, exome sequencing, tumor studies, and functional investigations of 4 generati...

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Detalles Bibliográficos
Autores principales: Nieminen, Taina T., O’Donohue, Marie-Françoise, Wu, Yunpeng, Lohi, Hannes, Scherer, Stephen W., Paterson, Andrew D., Ellonen, Pekka, Abdel-Rahman, Wael M., Valo, Satu, Mecklin, Jukka-Pekka, Järvinen, Heikki J., Gleizes, Pierre-Emmanuel, Peltomäki, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155505/
https://www.ncbi.nlm.nih.gov/pubmed/24941021
http://dx.doi.org/10.1053/j.gastro.2014.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155505/
https://www.ncbi.nlm.nih.gov/pubmed/24941021
http://dx.doi.org/10.1053/j.gastro.2014.06.009

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