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An atomic model of brome mosaic virus using direct electron detection and real-space optimization

Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisition, image pro...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Hryc, Corey F., Bammes, Benjamin, Afonine, Pavel V., Jakana, Joanita, Chen, Dong-Hua, Liu, Xiangan, Baker, Matthew L., Kao, Cheng, Ludtke, Steven J., Schmid, Michael F., Adams, Paul D., Chiu, Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155512/
https://www.ncbi.nlm.nih.gov/pubmed/25185801
http://dx.doi.org/10.1038/ncomms5808